Study on the clinical effect of preoperative shunt in the treatment of brain tumor with hydrocephalus and the monitoring value of intracranial pressure in patients
术前分流术治疗脑肿瘤合并脑积水的临床效果及患者颅内压监测值研究

摘要

目的 分析脑肿瘤合并脑积水中术前分流术的干预效果。方法 选择近2年（2020年1月-2022年2月）本院收治的脑肿瘤合并脑积水患者90例，回顾临床资料，将采用腰椎穿刺引流治疗的45例作为对照组，采用脑室-腹腔分流术治疗的45例患者作为观察组，对比两组临床疗效。结果 观察组术后7、14d测定的颅内压值更低，脑脊液SP100蛋白水平更低，与对照组相比差异有统计学意义（P<0.05）；观察组治疗总有效率更高，并发症率更低，与对照组相比差异有统计学意义（P<0.05）；术后14d，观察组GOS评分更高，KPS评分更高，与对照组相比差异有统计学意义（P<0.05）。结论 对脑肿瘤合并脑积水患者实施术前分流术有助于稳定颅内压，降低脑脊液SP100蛋白，帮助患者更好恢复，而实施脑室-腹腔分流术能进一步提高临床疗效，减少并发症的发生，可获得更好的预后效果，临床应用价值确切。

Abstract

Objective: To analyze the intervention effect of preoperative shunt in brain tumor with hydrocephalus.
Methods: 90 patients with brain tumor and hydrocephalus admitted to our hospital in recent 2 years (January 2020 February 2022) were selected. The clinical data were reviewed. 45 patients treated with lumbar puncture and drainage were taken as the control group, and 45 patients treated with ventriculoperitoneal shunt were taken as the observation group. The clinical effects of the two groups were compared.
Results: The intracranial pressure measured 7 and 14 days after operation in the observation group was lower, and the level of cerebrospinal fluid SP100 protein was lower than that in the control group (P<0.05); The total effective rate was higher and the complication rate was lower in the observation group than in the control group (P<0.05); On the 14th day after operation, the GOS score and KPS score of the observation group were higher than those of the control group (P<0.05).
Conclusion  : Preoperative shunt is helpful to stabilize intracranial pressure, reduce cerebrospinal fluid SP100 protein, and help patients recover better in patients with brain tumors and hydrocephalus, while ventriculoperitoneal shunt can further improve clinical efficacy, reduce complications, obtain better prognosis, and has definite clinical application value.